Article
Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiome.
Microbiome - 8 Feb 2017
Manor Ohad, Borenstein Elhanan
Abstract excerpt
BACKGROUND: Recent metagenomic analyses of the human gut microbiome identified striking variability in its taxonomic composition across individuals. Notably, however, these studies often reported marked functional uniformity, with relatively little variation in the microbiome's gene composition or in its overall metabolic capacity. RESULTS: Here, we address this surprising discrepancy between taxonomic and...
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