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Intraperitoneal administration of carcinoembryonic antigen-directed CAR-T cells is a robust delivery route for effective treatment of peritoneal carcinomatosis from colorectal cancer

2023-03-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Peritoneal carcinomatosis from colorectal cancer is a highly challenging disease to treat, and as such constitutes a pressing issue in medicine. Adoptive transfer of chimeric antigen receptor-T (CAR-T) cells has shown impressive efficacy in hematologic malignancies, though the approach has been less effective in solid tumors when delivered via intravenous (i.v.)...

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Literature Corpus work
f336e9e4-f711-54fc-bb63-db3da3eff7b9
DOI
10.21203/rs.3.rs-2651565/v1
Open publication

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Intraperitoneal administration of carcinoembryonic antigen-directed CAR-T cells is a robust delivery route for effective treatment of peritoneal carcinomatosis from colorectal cancerDOI 10.21203/rs.3.rs-2651565/v1
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