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SARS CoV-2 escape variants exhibit differential infectivity and neutralization sensitivity to convalescent or post-vaccination sera

2021-02-24

Abstract excerpt

<h4>SUMMARY</h4> Towards eradicating COVID19, developing vaccines that induce high levels of neutralizing antibodies is a main goal. As counter measurements, viral escape mutants rapidly emerge and potentially compromise vaccine efficiency. Herein we monitored ability of convalescent or Pfizer-BTN162b2 post-vaccination sera to neutralize wide-type SARS-CoV2 or its UK-B.1.1.7 and SA-B.1.351 variants. Relative to co...

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Identifiers and source

Literature Corpus work
f3273442-8f00-5b4b-b402-b08417f1ffb3
DOI
10.1101/2021.02.22.21252002
Open publication

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SARS CoV-2 escape variants exhibit differential infectivity and neutralization sensitivity to convalescent or post-vaccination seraDOI 10.1101/2021.02.22.21252002
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