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Article

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Cell - 29 Apr 2021

Garcia-Beltran Wilfredo F, Lam Evan C, St Denis Kerri, Nitido Adam D, Garcia Zeidy H, Hauser Blake M, Feldman Jared, Pavlovic Maia N, Gregory David J, Poznansky Mark C, Sigal Alex, Schmidt Aaron G, Iafrate A John, Naranbhai Vivek, Balazs Alejandro B

Abstract excerpt

Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2. However, ongoing surveillance has revealed the emergence of variants harboring mutations in spike, the main target of neutralizing antibodies. To understand the impact of these variants, we evaluated the neutralization potency of 99 individuals that received one or two doses of either BNT162b2 or mRNA-1273 vaccines against...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33743213
DOI: 10.1016/j.cell.2021.03.013
PMCID: PMC7953441

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