Article

Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera

2021-01-13

Abstract excerpt

<title>Abstract</title> <p>Rapidly spreading variants of SARS-CoV-2 that have arisen in the United Kingdom and South Africa share the spike N501Y substitution, which is of particular concern because it is located in the viral receptor binding site for cell entry and increases binding to the receptor. We generated isogenic N501 and Y501 SARS-CoV-2. Twenty human sera from the mRNA-based vaccine BNT162b2 trial exhib...

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Literature Corpus work: 4ea5cb20-707e-563a-8d2a-1bf077ab0453
DOI: 10.21203/rs.3.rs-143532/v1

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