Article
SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera.
Cell host & microbe - 14 Apr 2021
Kuzmina Alona, Khalaila Yara, Voloshin Olga, Keren-Naus Ayelet, Boehm-Cohen Liora, Raviv Yael, Shemer-Avni Yonat, Rosenberg Elli, Taube Ran
Abstract excerpt
Toward eradicating the COVID-19 pandemic, vaccines that induce high humoral and cellular immune responses are essential. However, SARS-CoV-2 variants have begun to emerge and raise concerns, as they may potentially compromise vaccine efficiency. Here, we monitored neutralization potency of convalescent or Pfizer-BTN162b2 post-vaccination sera against pseudoviruses displaying spike proteins derived from wild-type...
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