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Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

2024-05-13

Abstract excerpt

<title>Abstract</title> <p>Background Neoadjuvant therapy (NAT) is increasingly being used for pancreatic ductal adenocarcinoma (PDAC) treatment. However, its specific effects on carcinoma cells and the tumor microenvironment (TME) are not fully understood. This study aims to investigate how NAT differentially impacts PDAC’s carcinoma cells and TME. Methods Spatial transcriptomics was used to compare gene express...

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Literature Corpus work
f31f7917-b0e8-509e-9fef-8f533eeae331
DOI
10.21203/rs.3.rs-4104258/v1
Open publication

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Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal AdenocarcinomaDOI 10.21203/rs.3.rs-4104258/v1
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