Article

The SARS-CoV-2 envelope (E) protein forms a calcium- and voltage-activated calcium channel

2022-10-11

Abstract excerpt

The function of ion channels is essential in the infectious cycle of many viruses. To facilitate viral uptake, maturation and export, viruses must modify the ionic balance of their host cells, in particular of calcium ions (Ca 2+ ). Viroporins encoded in the viral genome play a key part in altering the cell’s ionic homeostasis. In SARS-Coronavirus-2 (SARS-CoV-2) – the causative agent of Covid-19 – the envelope (E...

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Literature Corpus work: f3199676-b2e5-5337-b036-0d4fd0148521
DOI: 10.1101/2022.10.11.511775

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