Article

The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes

2022-12-20

Abstract excerpt

<h4>ABSTRACT</h4> The exon junction complex (EJC) plays key roles throughout the lifespan of RNA and is particularly relevant in the nervous system. We investigated the roles of two EJC members, the paralogs MAGOH and MAGOHB, with respect to brain tumor development. High MAGOH/MAGOHB expression was observed in 14 tumor types; glioblastoma (GBM) showed the greatest difference compared to normal tissue. Increased M...

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Literature Corpus work: f31269a0-ce40-528c-b89a-a18e7bc681d2
DOI: 10.1101/2022.12.20.521107

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The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genesDOI 10.1101/2022.12.20.521107Read

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