Article

DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network

2022-12-21

Abstract excerpt

Genetic dissection of neuropsychiatric disorders can potentially reveal novel therapeutic targets. While genome-wide association studies (GWAS) have tremendously advanced our understanding, we approach a sample size bottleneck (i.e., the number of cases needed to identify >90% of all loci is impractical). Therefore, computationally enhancing GWAS on existing samples may be particularly valuable. Here, we describe...

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Literature Corpus work: f30fd21f-1405-583c-9760-65dd82e01fd1
DOI: 10.1101/2022.12.20.521277

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