Article
GenNet framework: interpretable deep learning for predicting phenotypes from genetic data.
Communications biology - 17 Sept 2021
van Hilten Arno, Kushner Steven A, Kayser Manfred, Ikram M Arfan, Adams Hieab H H, Klaver Caroline C W, Niessen Wiro J, Roshchupkin Gennady V
Abstract excerpt
Applying deep learning in population genomics is challenging because of computational issues and lack of interpretable models. Here, we propose GenNet, a novel open-source deep learning framework for predicting phenotypes from genetic variants. In this framework, interpretable and memory-efficient neural network architectures are constructed by embedding biologically knowledge from public databases, resulting in...
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