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cis-Aconitic Acid Derived from Clostridium sporogenes Attenuates Colitis via Targeting of Neutrophil TREM1

2025-12-16

Abstract excerpt

<title>Abstract</title> <p>Inflammatory bowel disease (IBD) remains a significant therapeutic challenge, with current agents plagued by suboptimal efficacy and safety issues. While gut microbiota dysbiosis is increasingly acknowledged as a key driver of IBD pathogenesis, the identification of functionally characterized, translationally applicable microbial-metabolic axes remains an unmet need. Here, we demonstrat...

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Identifiers and source

Literature Corpus work
f29c6280-f4a4-59b8-a4ae-f6040d7e498e
DOI
10.21203/rs.3.rs-8269242/v1
Open publication

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cis-Aconitic Acid Derived from Clostridium sporogenes Attenuates Colitis via Targeting of Neutrophil TREM1DOI 10.21203/rs.3.rs-8269242/v1
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