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Clostridium sporogenes -derived metabolites protect mice against colonic inflammation

14 Oct 2024

Abstract excerpt

Gut microbiota-derived metabolites play a pivotal role in the maintenance of intestinal immune homeostasis. Here, we demonstrate that the human commensal Clostridium sporogenes possesses a specific metabolic fingerprint, consisting predominantly of the tryptophan catabolite indole-3-propionic acid (IPA), the branched-chain acids (BCFAs) isobutyrate and isovalerate and the short-chain fatty acids (SCFAs) acetate...

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PMID: 39397690
DOI: 10.1080/19490976.2024.2412669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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