Article

Microbial Assimilatory Sulfate Reduction-Mediated H2S: An Overlooked Role in Crohn's Disease Development

2024-04-02

Abstract excerpt

<title>Abstract</title> <p>Background H<sub>2</sub>S imbalances in the intestinal tract trigger Crohn's disease (CD), a chronic inflammatory gastrointestinal disorder characterized by microbiota dysbiosis and barrier dysfunction. However, a comprehensive understanding of H<sub>2</sub>S generation in the gut, and the contributions of both microbiota and host to systemic H<sub>2</sub>S levels in CD, remain to be e...

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Literature Corpus work: 599ce1e3-c835-5c63-8780-dd11f5b587eb
DOI: 10.21203/rs.3.rs-4176488/v1

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