Article

«Enzymatic Landscape» of the Gut Microbiome in Obese Patients

2022-08-25

Abstract excerpt

Indole and indole-3-lactate are known dominant microbial tryptophan catabolites (MICT). In obesity, the fecal indole concentration corresponds to the normal one, and that of indole-3-lactate significantly decreases along with other MICT, while it increases in blood plasma. During the analysis of the «enzymatic landscape» of the intestinal microbiota we find an almost twofold increase in the correlation...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f28750db-efc4-5911-8be6-353b8bd2e83a
DOI: 10.20944/preprints202208.0436.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

«Enzymatic Landscape» of the Gut Microbiome in Obese PatientsDOI 10.20944/preprints202208.0436.v1Read

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversitySemantic proximity Read

Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples Of Healthy IndividualsSemantic proximity Read

Indoles as gut microbial pharmaco-metabolites : targets, mechanisms and consequences for obesity and cardiometabolic diseasesSemantic proximity Read

Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico AnalysisSemantic proximity Read

Indoles: metabolites produced by intestinal bacteria capable of controlling liver disease manifestationSemantic proximity Read

Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in RatsSemantic proximity Read

Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogensSemantic proximity Read

Microbial lactate utilisation and the stability of the gut microbiomeSemantic proximity Read

Substrate availability and dietary fibre regulate metabolism of tryptophan by human gut microbesSemantic proximity Read

Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan MetabolismSemantic proximity Read

Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feedingSemantic proximity Read

Regulation of tryptophan-indole metabolic pathway in Porphyromonas gingivalis virulence and microbiota dysbiosis in periodontitisSemantic proximity Read