Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of tryptophan-indole metabolic pathway in Porphyromonas gingivalis virulence and microbiota dysbiosis in periodontitis

26 Feb 2025

Abstract excerpt

Pathogenesis of periodontitis is marked by microbiota dysbiosis and disrupted host responses. Porphyromonas gingivalis is a keystone pathogen of periodontitis which expresses various crucial virulence factors. This study aimed to clarify the role and mechanisms of P. gingivalis tryptophan-indole metabolic pathway in the pathogenesis of periodontitis. This study showed that periodontitis patients exhibited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gut microbiota and health
Share to Oral microbiology and periodontitis research
Share to Salivary Gland Disorders and Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40011497
DOI: 10.1038/s41522-025-00669-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of tryptophan-indole metabolic pathway in Porphyromonas gingivalis virulence and microbiota dysbiosis in periodontitisPMID 40011497Read ↗

Transposase-Associated Variation near tnaA in Porphyromonas gingivalis Is Linked to Indole Production and Virulence-Associated Gene Expression.Semantic proximity Read ↗

Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum LineSemantic proximity Read ↗

Contribution of −Omics Technologies in the Study of Porphyromonas gingivalis during Periodontitis Pathogenesis: A MinireviewSemantic proximity Read ↗

<i>Porphyromonas gingivalis</i>: Major Periodontopathic Pathogen OverviewSemantic proximity Read ↗

Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico AnalysisSemantic proximity Read ↗

Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalisSemantic proximity Read ↗

Modulatory Mechanisms of Pathogenicity in Porphyromonas gingivalis and Other Periodontal PathobiontsSemantic proximity Read ↗

Identification and molecular characterization of tryptophanase encoded by tnaA in Porphyromonas gingivalis.Semantic proximity Read ↗

Tryptophan as a Central Hub for Host/Microbial SymbiosisSemantic proximity Read ↗

Mapping the pathogenesis of periodontitis: a new look.Semantic proximity Read ↗

Metabolic crosstalk regulates Porphyromonas gingivalis colonization and virulence during oral polymicrobial infectionSemantic proximity Read ↗

Host‐microbe interactions: Profiles in the transcriptome, the proteome, and the metabolomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.