Article

Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogens

2026-01-29

Abstract excerpt

Indole-3-acetic acid (IAA) is a tryptophan-derived gut microbial metabolite with reported anti-inflammatory activities, but the organisms and anaerobic pathways that support robust production remain unclear. Screening 206 human gut bacterial isolates by LC-MS revealed that IAA production is rare: only five strains exceeded the limit of quantitation, and high-capacity production was confined to the acetogens Blaut...

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Literature Corpus work: 3a7d917c-6d1c-5a78-90dd-91bd5d4fd5e0
DOI: 10.64898/2026.01.29.702580

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Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogensDOI 10.64898/2026.01.29.702580Read

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