Article

Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility

2019-11-04

Abstract excerpt

<h4>SUMMARY</h4> We developed ASTAR-Seq (Assay for Single-cell Transcriptome and Accessibility Regions) integrated with automated microfluidic chips, which allows for parallel sequencing of transcriptome and chromatin accessibility within the same single-cell. Using ASTAR-Seq, we profiled 192 mESCs cultured in serum+LIF and 2i medium, 424 human cell lines including BJ, K562, JK1, and Jurkat, and 480 primary cells...

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Literature Corpus work: f27807eb-183c-5e70-820e-394c77f06c2d
DOI: 10.1101/829960

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