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Snapshots of <i>Pseudomonas aeruginosa</i> SOS response activation complex reveal structural prerequisites for LexA engagement and cleavage

2024-03-23

Abstract excerpt

Antimicrobial resistance represents a major threat to human health and Pseudomonas aeruginosa stands out among the pathogens responsible for this emergency. The SOS response to DNA damage plays a pivotal role in bacterial evolution, driving the development of resistance mechanisms and influencing the adaptability of bacterial populations to challenging environments, particularly in the context of antibiotic expos...

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Literature Corpus work
f24ad0bd-f08e-5336-b69c-70ebc7fb5f4b
DOI
10.1101/2024.03.22.585941
Open publication

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Snapshots of <i>Pseudomonas aeruginosa</i> SOS response activation complex reveal structural prerequisites for LexA engagement and cleavageDOI 10.1101/2024.03.22.585941
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