Article

A teneurin-3 microphthalmia mutation disrupts trans adhesion for specific alternative splicing isoforms

2025-03-04

Abstract excerpt

Microphthalmia (MCOP) is a developmental eye disorder in which one or both eyes are abnormally small. This condition is often accompanied by cognitive impairments. Teneurin-3, a cell adhesion molecule with important functions in axon pathfinding and synaptic organization, has been repeatedly implicated with MCOP, suggesting its potential role in the etiology of this complex developmental disorder. It was previousl...

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Literature Corpus work: f2445d7d-c866-526e-a019-d28d55c3a06f
DOI: 10.1101/2025.02.28.640769

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