Article
Rapid functional analysis in Xenopus oocytes of Po protein adhesive interactions.
Neurochemical research - 1 Jun 2001
Yoshida M, Colma D R
Abstract excerpt
We have developed a coupled Xenopus oocyte expression system for evaluating the functional effects of mutations in known or suspected adhesion molecules, which allows for a very rapid assessment of intercellular adhesion. As a model protein, we first used Protein zero (Po), an adhesion molecule that mediates self-adhesion of the Schwann cell plasma membrane to form compact myelin in the mammalian PNS. A wide...
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