Article

Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation

2025-06-02

Abstract excerpt

<title>Abstract</title> <p>The leukocyte common antigen related receptor (LAR) is a member of the LAR receptor protein tyrosine phosphatase (RPTP) family of synaptic adhesion molecules that contribute to the proper alignment and specialization of synaptic connections in the mammalian brain. LAR-RPTP members have been genetically associated with neuropsychiatric disorders, but the molecular consequences of genetic...

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Literature Corpus work: 36a2c0ef-2fe8-5187-bb9a-8a9671d8208c
DOI: 10.21203/rs.3.rs-5928514/v1

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