Article

Cross-species Transcriptomic Network Analysis Reveals Links Between Ribosomal Protein Mutation and Cancer

2020-12-11

Abstract excerpt

Ribosomal proteins (RPs) are critical to all cellular operations through their key roles in ribosome biogenesis and translation, as well as their extra-ribosomal functions. Leveraging previously identified RP mutants we characterised the RP macro transcriptome and sought to compare it with transcriptomes of pathologies associated with failures of ribosomal function, cancer and Zika virus (ZIKV). Single gene-based...

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Literature Corpus work: f22ff8f2-3ca7-58f1-a6a4-1821f84d1dbf
DOI: 10.1101/2020.12.11.420604

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