Role of ribosomal protein mutations in tumor development (Review).

Abstract excerpt

Ribosomes are cellular machines essential for protein synthesis. The biogenesis of ribosomes is a highly complex and energy consuming process that initiates in the nucleolus. Recently, a series of studies applying whole-exome or whole-genome sequencing techniques have led to the discovery of ribosomal protein gene mutations in different cancer types. Mutations in ribosomal protein genes have for example been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anemia, Diamond-Blackfan
• Share to Carcinogenesis
• Share to Gene Regulatory Networks