Article

Characterisation of guanylin and uroguanylin in the digestive system

2019-01-01

Abstract excerpt

Guanylin and uroguanylin are closely related peptides originating from the intestinal mucosa with established roles in salt and water homeostasis and the regulation of gut physiology. These hormones are secreted as the propeptides, ProGuanylin and ProUroguanylin, and post- translationally processed into active peptides in the intestinal lumen. Those active peptides activate the guanylyl cyclase C (GC-C) receptor f...

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Literature Corpus work: f20d410d-688c-5aa2-8bd1-99edfcace83a
DOI: 10.17863/cam.38505

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