Article

Early Elevated IFNα Identified as the Key Mediator of HIV Pathogenesis and its low level a Hallmark of Elite Controllers

2023-05-11

Abstract excerpt

<title>Abstract</title> Advances in HIV therapy came from understanding its replication. Further progress toward “functional cure” - no therapy needed as found in Elite Controllers (EC) - may come from insights in pathogenesis and avoidance by EC. Here we show that all immune cells from HIV infected persons are impaired in non-EC, but not in EC. Since HIV infects few cell types, these results suggest an additi...

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Literature Corpus work: f2097e24-a170-5dd2-a83b-1e68ab39566d
DOI: 10.21203/rs.3.rs-2813601/v1

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