Article

Comprehensive analysis of HIV elite controllers’ and progressors’ transcriptional profiles from CD8 <sup>+</sup> T lymphocytes demonstrates heterogeneity of pathways and master regulators, which may be essential for disease nonprogression

2020-10-20

Abstract excerpt

<h4>ABSTRACT</h4> Cytotoxic and noncytotoxic CD8 + T lymphocyte responses are essential for the control of HIV infection. Understanding the mechanisms underlying HIV control in elite controllers (ECs), who do not progress to AIDS for many years without treatment, may facilitate the development of new effective therapeutic strategies. We performed a comprehensive analysis of the transcriptional profiles of CD8...

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Literature Corpus work: 767609be-87d9-5535-81cd-3be0a51ac4a2
DOI: 10.1101/2020.10.19.346528

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Comprehensive analysis of HIV elite controllers’ and progressors’ transcriptional profiles from CD8 <sup>+</sup> T lymphocytes demonstrates heterogeneity of pathways and master regulators, which may be essential for disease nonprogressionDOI 10.1101/2020.10.19.346528Read

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