Article
Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer.
Proteomics - 1 Feb 2011
Li Li-Ping, Lu Chun-Hua, Chen Zhi-Peng, Ge Feng, Wang Tong, Wang Wei, Xiao Chuan-Le, Yin Xin-Feng, Liu Langxia, He Jian-Xing, He Qing-Yu
Abstract excerpt
Subcellular proteomics was used to compare the protein profiles between human lung adenocarcinoma A549 cells and human bronchial epithelial (HBE) cells. In total, 106 differential proteins were identified and the altered expression levels of partial identified proteins were confirmed by Western blot analysis. Importantly, pathway analysis and biological validation revealed epithelial-mesenchymal transition (EMT)...
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