Article

Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants

2021-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Vaccine hesitancy and continuing emergence of SARS-CoV-2 variants of concern that may escape vaccine-induced immune responses highlight the urgent need for effective COVID-19 therapeutics. Monoclonal antibodies used in the clinic have varying efficacies against distinct SARS-CoV-2 variants; thus, there is considerable interest in engineered ACE2 peptides with augmented binding affinities for SAR...

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Literature Corpus work: f201182e-049d-5b76-ab38-d17f19227e31
DOI: 10.1101/2021.12.21.473668

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