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Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting

2023-10-02

Abstract excerpt

<h4>Background</h4> Maternal exposure to environmental chemicals can cause adverse health effects in offspring. Mounting evidence supports that these effects are influenced, at least in part, by epigenetic modifications. <h4>Objective</h4> We examined tissue- and sex-specific changes in DNA methylation (DNAm) associated with human-relevant lead (Pb) and di(2-ethylhexyl) phthalate (DEHP) exposure during perinatal...

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Literature Corpus work
f1d7972a-3fe9-575f-a9a4-9334b23c386d
DOI
10.1101/2023.09.29.560131
Open publication

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Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic ImprintingDOI 10.1101/2023.09.29.560131
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