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Genome-Wide DNA Methylation Profiles of Neurodevelopmental Disorder Genes in Mouse Placenta and Fetal Brain Following Prenatal Exposure to Polychlorinated Biphenyls

2021-05-27

Abstract excerpt

<h4>Background</h4> Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as environmental risk factors for neurodevelopmental disorders (NDD), including autism spectrum disorders (ASD). <h4>Objective</h4> We examined the effects of prenatal exposure to a human-relevant mixture of PCBs on the DNA methylome of fetal mouse brain and placenta to determine if there was a shared subset of diffe...

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Literature Corpus work
dd9f0956-d9db-54ce-bf12-4b7b77623796
DOI
10.1101/2021.05.27.446011
Open publication

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Genome-Wide DNA Methylation Profiles of Neurodevelopmental Disorder Genes in Mouse Placenta and Fetal Brain Following Prenatal Exposure to Polychlorinated BiphenylsDOI 10.1101/2021.05.27.446011
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