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Perinatal exposure to lead results in altered DNA methylation in adult mouse liver and blood: Implications for target versus surrogate tissue use in environmental epigenetics

2019-10-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> DNA methylation is a critical epigenetic mechanism linking early developmental environment to long-term health. In humans, the extent to which toxicant-induced changes in DNA methylation in surrogate tissues, such as blood, mirror those in the target tissues is unclear. The Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription (TaRGET II) con...

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Literature Corpus work
f7a3f92e-9703-54fb-bbfa-6a9626b2e149
DOI
10.1101/783209
Open publication

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Perinatal exposure to lead results in altered DNA methylation in adult mouse liver and blood: Implications for target versus surrogate tissue use in environmental epigeneticsDOI 10.1101/783209
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