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Article

Sex-Specific Deflection of Age-Related DNA Methylation and Gene Expression in Mouse Heart by Perinatal Toxicant Exposures

2024-04-28

Abstract excerpt

<h4>Background</h4> Global and site-specific changes in DNA methylation and gene expression are associated with cardiovascular aging and disease, but how toxicant exposures during early development influence the normal trajectory of these age-related molecular changes, and whether there are sex differences, has not yet been investigated. <h4>Objectives</h4> We used an established mouse model of developmental exp...

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Literature Corpus work
7c372166-e196-5bfa-b991-d916f206fd15
DOI
10.1101/2024.04.25.591125
Open publication

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Sex-Specific Deflection of Age-Related DNA Methylation and Gene Expression in Mouse Heart by Perinatal Toxicant ExposuresDOI 10.1101/2024.04.25.591125
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