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Exposure to Phthalate, an Endocrine Disrupting Chemical, Alters the First Trimester Placental Methylome and Transcriptome in Women

11 Apr 2018

Abstract excerpt

Phthalates are known endocrine disruptors and associated with decreased fecundity, pregnancy loss, and adverse obstetrical outcomes, however the underlying mechanisms remain to be established. Environmental factors can influence gene expression and cell function by modifying epigenetic marks, impacting the developing embryo as well as future generations of offspring. The impact of phthalates on placental gene...

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Birth, Development, and Health
Effects and risks of endocrine disrupting chemicals
Epigenetics and DNA Methylation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29666409
DOI: 10.1038/s41598-018-24505-w

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