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Human macrophage polarization determines bacterial persistence of <i>Staphylococcus aureus</i> in a liver-on-chip-based infection model

2021-11-19

Abstract excerpt

Infections with Staphylococcus aureus ( S. aureus ) have been reported from various organs ranging from asymptomatic colonization to severe infections and sepsis associated with multiple organ dysfunction. Although considered an extracellular pathogen, S. aureus can invade and persist in professional phagocytes such as monocytes and macrophages. Its capability to persist and manipulate phagocytes is considered...

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Literature Corpus work
f1d55c9b-1886-5d44-ac5f-a3a319bda80f
DOI
10.1101/2021.11.19.469246
Open publication

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Human macrophage polarization determines bacterial persistence of <i>Staphylococcus aureus</i> in a liver-on-chip-based infection modelDOI 10.1101/2021.11.19.469246
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