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Functional Hepatocyte Culture and its Application to Cell Therapies

1 Nov 2006

Abstract excerpt

Since Berry and Friend developed methods to isolate hepatocytes from the liver by a collagenase digestion technique in 1969, studies in laboratory animals have demonstrated that hepatocyte transplantation could potentially be used for the treatment of liver failure and inborn errors of liver-based metabolism. Healthy human hepatocytes are an ideal source for hepatocyte transplantation; however, their relative...

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PMID: 17299989
DOI: 10.3727/000000006783981332

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