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Landscape of tumor-infiltrating immune cells in human immunogenic cancers:B cells are inversely associated with CD8T cells, but positively correlated with Treg cells

2019-05-17

Abstract excerpt

The composition of tumor-infiltrating immune cells may be a strong predictor of cancer treatment responses and survival outcomes. While B cells have been suggested to suppress T cell cytotoxicity in preclinical studies, it has been less understood whether B cells will exert immune-regulatory roles in human cancers. We explored immune cell landscapes in six human immunogenic cancers, including bladder cancer, head...

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Literature Corpus work
f1919262-a307-50c4-8b59-9c3cf8d060f8
DOI
10.1101/641712
Open publication

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Landscape of tumor-infiltrating immune cells in human immunogenic cancers:B cells are inversely associated with CD8T cells, but positively correlated with Treg cellsDOI 10.1101/641712
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