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Article

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy.

Genome biology - 22 Aug 2016

Li Bo, Severson Eric, Pignon Jean-Christophe, Zhao Haoquan, Li Taiwen, Novak Jesse, Jiang Peng, Shen Hui, Aster Jon C, Rodig Scott, Signoretti Sabina, Liu Jun S, Liu X Shirley

Abstract excerpt

BACKGROUND: Understanding the interactions between tumor and the host immune system is critical to finding prognostic biomarkers, reducing drug resistance, and developing new therapies. Novel computational methods are needed to estimate tumor-infiltrating immune cells and understand tumor-immune interactions in cancers. RESULTS: We analyze tumor-infiltrating immune cells in over 10,000 RNA-seq samples across 23...

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Source

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Identifiers

PMID: 27549193
DOI: 10.1186/s13059-016-1028-7
PMCID: PMC4993001

Genes

CTLA4
MAGEA3
SPAG5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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