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Article

Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development

15 Jan 2018

Abstract excerpt

An increasing body of evidence points to significant spatio-temporal differences in early placental development between mouse and human, but a detailed comparison of placentae in these two species is missing. We set out to compare placentae from both species across gestation, with a focus on trophoblast progenitor markers. We found that CDX2 and ELF5, but not EOMES, are expressed in early post-implantation...

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PMID: 29361559
DOI: 10.1242/dev.156273

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