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Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer

2024-04-27

Abstract excerpt

Individuals with retinal degenerative diseases face significant obstacles in restoring normal vision due to the inability to regenerate degenerated retinal cells. While retinal neurons can be regenerated from Müller glia (MG) in cold-blooded vertebrates, this regenerative ability is lacking in mammals, indicating the limited competence of mammalian MG for retinal regeneration. In this study, we elucidate the role...

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Identifiers and source

Literature Corpus work
f17b34c0-66db-5f23-9a93-9b698353b02a
DOI
10.1101/2024.04.23.590652
Open publication

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Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transferDOI 10.1101/2024.04.23.590652
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