Article

Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice

2022-03-27

Abstract excerpt

<h4>Summary</h4> Current concepts regarding the biology of aging are based on studies aimed at identifying factors regulating natural lifespan. However, lifespan as a sole proxy measure for aging can be of limited value because it may be restricted by specific sets of pathologies, rather than by general physiological decline. Here, we employed large-scale phenotyping to analyze hundreds of phenotypes and thousand...

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Literature Corpus work: f16b9a38-539e-543a-a698-8be55c434fbb
DOI: 10.1101/2022.03.25.485824

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