Article

The piRNA Response to Retroviral Invasion of the Koala Genome

2019-04-05

Abstract excerpt

Transposons are ubiquitous mobile elements with the potential to trigger genome instability and mutations linked to diseases 1,2 . Antisense piRNAs guide an adaptive genome immune system that silences established transposons during germline development 3 , but how the germline responds to new genome invaders is not understood. The KoRV retrovirus infects somatic and germline cells and is sweeping through wild ko...

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Literature Corpus work: f1513d29-2484-5317-ba05-c431e7e5e7f3
DOI: 10.1101/599852

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