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Transmission, Evolution, and Endogenization: Lessons Learned from Recent Retroviral Invasions

13 Dec 2017

Abstract excerpt

are defined by the ability to reverse transcribe an RNA genome into DNA that integrates into the host cell genome during the intracellular virus life cycle. Exogenous retroviruses (XRVs) are horizontally transmitted between host individuals, with disease outcome depending on interactions between the retrovirus and the host organism. When retroviruses infect germ line cells of the host, they may become endogenous...

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PMID: 29237726
DOI: 10.1128/mmbr.00044-17

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