Article

A Proteomic Profile of the Ocular Phenome: Systemic Signatures, Predictive Value, and Causal Insights Across 131 Ocular Diseases and Traits

2025-07-31

Abstract excerpt

Vision loss remains one of the most pervasive and preventable global health burdens, yet ophthalmology has yet to fully benefit from molecular precision medicine. Unlike oncology and cardiometabolic diseases, the early detection and subtyping of eye disorders are hindered by limited access to intraocular tissues and a prevailing belief that the blood-ocular barrier precludes systemic biomarker utility. To systemat...

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Literature Corpus work: f142973d-ff77-5dfb-a253-cc05b7822e64
DOI: 10.1101/2025.07.31.25332495

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