Article
Interneuron diversity in the human dorsal striatum
2023-03-23
Abstract excerpt
Deciphering the striatal interneuron diversity is key to understanding the basal ganglia circuit and to untangle the complex neurological and psychiatric diseases affecting this brain structure. We performed single-nucleus RNA-sequencing (snRNA-seq) of postmortem human caudate nucleus (CN) and putamen (Pu) samples to elucidate the diversity and abundance of interneuron populations and their transcriptional structu...
Topics
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- Adipose Tissue and Metabolism
- Genetic Mapping and Diversity in Plants and Animals
- Genomics and Chromatin Dynamics
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Nuclear Receptors and Signaling
- Parkinson's Disease Mechanisms and Treatments
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- f119ebd6-6e1f-56fd-a0f3-d1769e8db8e8
- DOI
- 10.1101/2023.03.22.533839
