Article

A conserved cell-type gradient across the human mediodorsal and paraventricular thalamus

2024-09-05

Abstract excerpt

The mediodorsal thalamus (MD) and adjacent midline nuclei are important for cognition and mental illness, but their cellular composition is not well defined. Using single-nucleus and spatial transcriptomics, we identified a conserved excitatory neuron gradient, with distinct spatial mapping of individual clusters. One end of the gradient was expanded in human MD compared to mice, which may be related to the expans...

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Identifiers and source

Literature Corpus work: e716bba9-2ee0-5287-8c5b-6401e30ebaec
DOI: 10.1101/2024.09.03.611112

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