Article

Alternative exon splicing reveals hidden mitochondrial targeting of PLIN3

2026-02-19

Abstract excerpt

Perilipin 3 (PLIN3) is a lipid droplet–associated protein implicated in cellular lipid metabolism. We characterize a previously unrecognized alternative splicing event in human PLIN3 . The generated transcript PLIN3B is detectable at the RNA level across human tissues and is modulated by antisense oligonucleotide–mediated splicing. Despite clear evidence for PLIN3B transcript expression, endogenous PLIN3B prote...

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Literature Corpus work: f1174038-df72-5ad4-99a8-d9f33f8d62c6
DOI: 10.64898/2026.02.18.706587

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