Article

Generation of Valvular Interstitial Cells from Human Pluripotent Stem Cells

2025-09-21

Abstract excerpt

Heart valves are living structures whose sophisticated functions are mediated by a specialized population of mesenchymal cells known as valvular interstitial cells (VICs). Given their central role in valve homeostasis, VICs represent a promising cell population for studying heart valve diseases and developing novel therapies to treat them. Here, we describe a strategy for generating VICs from human pluripotent ste...

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Literature Corpus work: f0f2e942-1f6a-5459-be18-0bf6eda53435
DOI: 10.1101/2025.09.17.676963

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