Article

Single haplotype admixture models using large scale HLA genotype frequencies to reproduce human admixture

2018-06-01

Abstract excerpt

The Human Leukocyte Antigen (HLA) is the most polymorphic region in humans. Anthropologists use HLA to trace populations’ migration and evolution. However, recent admixture between populations masks the ancestral haplotype frequency distribution. We present an HLA-based method based on high-resolution HLA haplotype frequencies to resolve population admixture using a non-negative matrix factorization formalism and...

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Literature Corpus work: f0dcf2ba-0e6e-5001-a3a3-7f4f7b08b206
DOI: 10.1101/336693

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