Article

Accurate Determination of Bacterial Abundances in Human Metagenomes Using Full-length 16S Sequencing Reads

2017-12-04

Abstract excerpt

DNA sequencing of PCR-amplified marker genes, especially but not limited to the 16S rRNA gene, is perhaps the most common approach for profiling microbial communities. Due to technological constraints of commonly available DNA sequencing, these approaches usually take the form of short reads sequenced from a narrow, targeted variable region, with a corresponding loss of taxonomic resolution relative to the full le...

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Literature Corpus work: f0d0b695-ff1d-573d-bb66-db12f7494924
DOI: 10.1101/228619

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